You probably have this app pre-installed so search for it first.
If not, in any case, install it via
apt install shutter.
Now, we will start using it.
Open the app Shutter, and go right to the preferences pane.
On the first page you might want to select automatically save file and automatically copy screenshot to clipboard like this:
And to keep the shutter programe from opening after we capture the screenshot you might want to uncheck the present main window after taking a screenshot option like this:
Now, the only part left is to bind it with shortcuts, we'll go to the keyboard settings, if you can't remember it's this one:
Go to the shortcuts menu, and create some:
Each of which is described as follows:
Note that these are the shutter options you can see full list from